Children and adults diagnosed with PCD depending on severity of clinical manifestations, are followed up at intervals of 1-6 months by the Pediatric pulmonology clinic of Makarios III hospital. Clinical management involves clinical evaluation/examination, assessment of lung function and exacerbation status as well as assessment of sputum microbiology. Patients are always referred to the physiotherapy department for respiratory physiotherapy evaluation. Patients are trained to implement appropriate physiotherapy techniques at home for daily mucus clearance as a maintenance measure of their respiratory wellbeing and reduction of treatment burden. The implemented physiotherapy techniques by the patients are reviewed at least annually by the physiotherapist. Acute exacerbations are treated with antibiotics (either oral or IV) according to sputum microbiology results, intensification of chest physiotherapy and if needed with inhaled bronchodilators and corticosteroids.

Patients with severe/frequent chest exacerbations may be prescribed with prophylactic antibiotics such as azithromycin on three days/week and if chronically colonized with pseudomonas also with nebulized colistin or tobramycin. For occasional recovery of pseudomonas in the sputum microbiology we follow an eradication protocol with systematic anti-pseudomonas antibiotics for 2-3 weeks (most commonly ciprofloxacin) followed by 3 months of nebulized colistin or tobramycin.

Patients with nutritional or growth deficiencies are also referred to the in-house nutritionist. Access to psychological and social support is also provided to patients dealing with frustration, fertility issues. During hospitalizations for iv treatments, Archbishop Makarios III hospital provides in house school services when required.